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Bioinformatics for Glycan Expression

Integrated Technology Resource for Biomedical Glycomics: Technological Research and Development Project IV, A Project funded by NIH


GLYcan Data Exchange (GLYDE) Standard

An XML-based data representation standard that faithfully captures essential structural details of a glycan moiety along with additional information (such as data provenance) to aid the interpretation and usage of glycan data, will facilitate the exchange of glycomics data across the scientific community.

To meet this need, we introduce a GLYcan Data Exchange (GLYDE) standard as an XML-based representation format to enable interoperability and exchange of glycomics data. The XML representation is compatible with the GlycO ontology and facilitates the computational processing of glycan structures. Furthermore, the natural tree structure of complex glycans finds an almost natural mapping with the tree structure of XML.

An online tool for the conversion of other representations to GLYDE format has been developed.

The following are available for use:


Funding: Bioinformatics of Glycan Expression (one of the four components of the "Integrated Technology Resource for Biomedical Glycomics," appox. $6 million+), National Institute of Health, July 1, 2003 - June 30, 2008.