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  </owl:Class>
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    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >This defines a broad class that includes any collection of data. It can hold other data collections, it can hold parameters, which are defined as atomic objects in ProPreO (i.e., parameters cannot be further subdivided.)

[Will &amp; Satya 02/15/06]</rdfs:comment>
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    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of parameters controlling the operation of the analyzer of a mass spectrometer

[James &amp; Satya: 02/24/05]</rdfs:comment>
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  </owl:Class>
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    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
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[James &amp; Satya: 03/27/05]</rdfs:comment>
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    >The simulation of data from input data. For example, simulation of a  theoretical spectrum from a chemical composition.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
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URL: www.ncbi.nlm.nih.gov/RefSeq/key.html 

[Dr. York &amp; Satya: 06/23/05]</rdfs:comment>
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    >The task of transforming one encoding type into another. For example, binary to ascii.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
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    <owl:versionInfo rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >TODO: Find out the various formats, softwares used...</owl:versionInfo>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection generated by a processing raw gel electrophoresis data.  This data will include, for example
1. Spot location
2. Spot Intensity
3. Spot Identity

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
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    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of computational parameters required to process ms or ms-ms data

[James &amp; Satya: 03/27/05]</rdfs:comment>
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    >A parameter that defines the units used to describe the intensity of a laser pulse</rdfs:comment>
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      <owl:Class rdf:ID="physical_units"/>
    </rdfs:subClassOf>
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    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection that is generated by a Spectrum Mill database search with ms, ms-ms data

[James &amp; Satya: 03/29/05]</rdfs:comment>
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    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >This describes the task of transforming a given glycan structure from one representation format into another. For example from LINUCS to GLYDE. 

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
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    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that is measured during an HPLC experiment - E.G. the detector signal intensity at a particular time.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="PDB_accession_number">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that specifies the unique identifier for a particular protein in the PDB database.
URL: http://www.rcsb.org/pdb/

[Dr. York &amp; Satya: 06/14/05]</rdfs:comment>
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      <owl:Class rdf:ID="protein_accession_number"/>
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    >The process of separating components by size-exclusion chromatography.</rdfs:comment>
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      <owl:Class rdf:ID="separate_by_chromatography"/>
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  </owl:Class>
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      <owl:Class rdf:ID="MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
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      <owl:Class rdf:ID="ESI_source"/>
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    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Electrospray source for flow rates &lt; 3 microlitres/min.

[James &amp; Satya: 02/24/05]</rdfs:comment>
  </owl:Class>
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    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Agilent_HPLC">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A High Performance Liquid Chromatograph manufactured by Agilent Technologies.

[James &amp; Satya: 01/31/05]</rdfs:comment>
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      <owl:Class rdf:ID="high_performance_liquid_chromatograph"/>
    </rdfs:subClassOf>
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  <owl:Class rdf:ID="Proteinlynx_micromass_ms-ms_survey_data_processing_parameters_collection">
    <rdfs:subClassOf rdf:resource="#MS_data_processing_parameter_collection"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The collection of processing parameters used by Proteinlynx when converting a ms/ms survey '.raw' file into a '.pkl' or a '.dta' file, when using Proteinlynx.

[James &amp; Satya: 04/01/05]</rdfs:comment>
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    <rdfs:subClassOf>
      <owl:Class rdf:ID="mass_spectrometer"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A mass spectrometer that can perform both MS and MS/MS analysis. 

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
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    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A single time-point generated by an HPLC experiment - This corresponds to a pair of parameters, the internal HPLC time and the detector signal at that time.</rdfs:comment>
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    <owl:equivalentClass>
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        <owl:onProperty>
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        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
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    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that describes the detection wavelength of the HPLC detector, which may be either an absorbance detector or a fluorescence detector.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
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        <owl:allValuesFrom>
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        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_instrumental_operating_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="transform_peptide_sequence_format">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >This describes the tranformation of a given peptide sequence from one format into another.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#tranform_representation_format"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_HCTplus_ion_trap_ms_raw_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_data_collection">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection used or generated by a high performance liquid chromatography experiment</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#process_associated_data_collection"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="quadrupole_analyzer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of MS analyzer</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="MS_analyzer"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="SemURI_instance_ID">
    <rdfs:subClassOf>
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    <rdfs:subClassOf>
      <owl:Class rdf:ID="SemURI_parameter"/>
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          <owl:ObjectProperty rdf:ID="has_SemURI_concept_ID"/>
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        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >0</owl:cardinality>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The second component of a semantic Universal Resource Identifier (semURI) module.  This identifies a specific instance (within the context of a provenance chain) of a SemURI concept.

It is important to note that the same SemURI_instance_ID can be used for two distinct instances of the same concept, as long as the two instances are not present at the same location of a single provenance chain.  This allows the SemURI_instance_ID to be short and still insures that the SemURI as a whole is unique.  Uniqueness stems from the entire SemURI, which consists of several SemURI modules.  That is, two SemURIs can be unique even if they share a common SemURI module, just as two words can be unique even if they share a common letter of series of letters.

[will &amp; satya 03/03/06]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_ultraflex_MALDI_TOF_mass_spectrometer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of MALDI-TOF mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
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  </owl:Class>
  <owl:Class rdf:ID="Micromass_Quatro_micro_triple_quadrupole_mass_spectrometer">
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        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="triple_quadrupole_mass_spectrometer"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="substance_identifier">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="substance_parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that identifies a molecule or molecular aggergate.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="isocratic_HPLC_pump">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC pump.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_pump"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="UV_spectrometer">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="analytical_instrument"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An instrument that measures the transmittance of ultraviolet light through a sample (usually a liquid).</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="standard_ESI_source">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ESI_source"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="bacteria">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A diverse group of prokaryotic organisms, distinct from the Archaea.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="procaryotic_organism"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="source_life-cycle-stage">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:ID="refers_to_material_continuant"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="life-cycle_form"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="biological_source_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="REFSEQ_protein_accession_number">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#protein_accession_number"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that specifies the unique identifier for a particular protein in the RefSeq system.
URL: www.ncbi.nlm.nih.gov/RefSeq/ 

[Dr. York &amp; Satya: 06/14/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="enzyme">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An enzyme is a protein or protein complex that catalyzes a specific set of chemical reactions.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="chemical_agent"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="protein"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="parent_ion">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ion"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An ion, generated in a mass spectrometer, that is subsequently dissociated into fragment ions in an MS/MS experiment</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#biological_source_parameter">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that describes some aspect of part of an organism that was used as the source of a biological_sample or biomolecule.  A biological source parameter refers to, for example, a species, organ, cell type, life-cycle stage, develomental stage, etc.  Within the context of ProPreO, biological source parameters are meant to describe  laboratory samples that are analyzed by or used in proteomics or glycoproteomics methods.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="biological_continuant"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#refers_to_material_continuant"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="LINUCS_ID">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that specifies the unique glycan identifier in SWEETDB. 
URL: http://www.glycosciences.de/sweetdb/index.php

[Dr. York &amp; Satya: 06/13/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="glycan_accession_number"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_esquire6000_ion_trap_ms_raw_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#chemical_agent">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#agent"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A chemical agent is a chemical or molecule (such as an enzyme) that implements or initiates a molecular process.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="quantify_components">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The complex task of quantifying the components of a mixture. This may involve, for example,
HPLC of the mixture (i.e. separate_by_HPLC) followed by computational peak picking and signal integration (i.e., quantify_data).</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="hybrid_task"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="MS_analyzer_TOF_type">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#refers_to_material_continuant"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="TOF_analyzer"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_analyzer_parameter"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >0</owl:cardinality>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the type of TOF analyzer. It may either be:
a) Reflectron
or
b) Linear

[James &amp; Satya: 02/24/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_HCT_ion_trap_ms_raw_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="MS_source">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="MS_component"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="operating_parameter">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that is used to control the execution of a task, such as a physical parameter required for recording a mass spectrum or a computational parameter for processing a data set.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#transform_data_format">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The task of transforming the format of data, usually creating a new data file with either new file format or data encoding.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="transform_data"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_buffer">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >0</owl:cardinality>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_instrumental_operating_parameter"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#refers_to_material_continuant"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:unionOf rdf:parseType="Collection">
              <owl:Class rdf:ID="solution"/>
              <owl:Class rdf:ID="solvent"/>
            </owl:unionOf>
          </owl:Class>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that identifies the elution buffer used in HPLC. A mixture of buffers is often prepared in a mixing device to form a time-dependent elution gradient.  

The HPLC_buffer parameter is a substance identifier, which points to an instance of "solution".  A "solution" is_described_by one or more mixture_component_descriptor(s), each of which has two parts:  the component_amount and a substance_identifier that specifies the identity of the component.  This is a flexible way of describing solutions.  For example, a solution can be described as a mixture of two other solutions (e.g., buffer A and buffer B), in which case the mixture_component_descriptor(s) each specify the identity and amount of each of these buffers.  Alternatively, a solution can be described according to the concentrations of its solutes (molecules), each of which is specified by a mixture_component_descriptor.   In this case, complete description of the solution requires that the solvent be specified using the property has_solvent, which points to an instance of the class "solvent".

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#substance_identifier"/>
  </owl:Class>
  <owl:Class rdf:ID="MS_source_ESI_capillary_voltage">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the voltage applied to the ESI capillary.

[James &amp; Satya: 02/24/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MS_source_ESI_parameter"/>
    <owl:equivalentClass>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
      </owl:Restriction>
    </owl:equivalentClass>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="electrical_potential_units"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="elemental_composition">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the identities of chemical elements and the number of atoms of each element that constitute a molecule.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >0</owl:cardinality>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="molecular_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="fragment_peptide_C_terminus_index">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#molecular_parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the index (within the parent protein) of the C- terminus of a fragment peptide.

[will &amp; satya 04/25/06]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#MS_analyzer_parameter">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="MS_instrumental_operating_parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the operating state of the mass spectrometer analyzer during data collection

[Will &amp; Satya 02/15/06]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_chromatogram_XML_format_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection (chromatogram) generated by an HPLC experiment - This describes, two-column data which are signal vs time. The data columns are in XML.

[James &amp; Satya: 03/29/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_chromatogram"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="absolute_amount">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the amount of a substance in absolute terms (total mass, total volume, total number of moles, as appropriate).

[will &amp; satya 04/13/06]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="substance_amount"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#process_associated_data_collection">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection that is classified according to the process that uses/creates/generates it.</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#data_collection"/>
  </owl:Class>
  <owl:Class rdf:ID="PEAKS_denovo_sequencing_results_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection produced by performing PEAKKS denovo sequecing.

[James &amp; Satya: 03/29/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="denovo_sequencing_output_data_collection"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="strong_anion_exchange_HPLC_column">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_column"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC column</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_Daltomics_mass_spectrometer_data_processing_application">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Application software developed by Bruker Daltonics for processing mass spectrometer data.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="MS_data_processing_application"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="flourescence_spectrometer">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#analytical_instrument"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A fluorescence spectrometer measures the intensity of light that is re-emitted by a fluorescent molecule.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_manual_injector">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_component"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An HPLC component that is used for manual injection of the sample onto the column.

[James &amp; Satya: 01/31/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="antibody_affinity_HPLC_column">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC column</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_column"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#computational_task">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A task involved in the processing of data by a computational application.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="task"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="MS_source_MALDI_number_of_laser_shots">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="MS_source_MALDI_parameter"/>
    </rdfs:subClassOf>
    <owl:equivalentClass>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#int"/>
      </owl:Restriction>
    </owl:equivalentClass>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the number of laser shots in a MALDI experiment.
This is a pure integer (no units).

[James &amp; Satya: 02/24/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >0</owl:cardinality>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="GycO_ID">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#glycan_accession_number"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that specifies the unique identifier for a glycan instance in glycan domain ontology: GlycO.
URL: http://lsdis.cs.uga.edu/projects/glycomics/glyco/

[Dr. York &amp; Satya: 06/13/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="database_search_results_Sequest_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#database_search_output_data_collection"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection that is generated by a Sequest database search with ms, ms-ms data

[James &amp; Satya: 03/29/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="experimental_ion_charge">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="MS_experimentally_measured_parameter"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="ion_charge"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the measured charge of a particular ion.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_excitation_wavelength">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:about="#length_units"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that describes the excitation  wavelength of a fluorescence HPLC detector.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_instrumental_operating_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_gradient_program">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of parameters that describe the solvent gradient for an HPLC run

[Dr. York &amp; Satya: 05/17/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_operating_parameter_collection"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_data_part"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="HPLC_gradient_time_point"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="MS_maxent3_iterations_per_ensemble_member_value">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_data_processing_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#triple_quadrupole_mass_spectrometer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem_mass_spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#tandem_mass_spectrometer"/>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_omniflex_MALDI_TOF_mass_spectrometer">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="Bruker_omniflex_MALDI_TOF_ms_raw_data"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MALDI-TOF_mass_spectrometer"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of MALDI-TOF mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#gel_electrophoresis_experimental_data_collection">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="experimentally_measured_data_collection"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="gel_electrophoresis_data_collection"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection generated by a gel electrophoresis experiment</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#isoelectric_point">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Describes the pH at which a zwitter ionic molecule has no charge also called pI.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#molecular_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="identify_components">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#hybrid_task"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The complex task of identifhying the components of a mixture. This may involve, for example, HPLC of the mixture (i.e. separate_by_HPLC) followed by computational peak picking and peak matching (i.e., classify_data).</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="record_ms_data">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:about="#MS_raw_data_native_format"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="record_raw_data"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Tthe physical task of running a mass spectrometer on a specific sample and recording the resulting spectra.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="electrical_charge_units">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#physical_units"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="potential_units">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter defining the physical units of potential, such as electrical potential, gravitational potential, etc.
Potentials generally have units "energy per amount", for example volts are Joules per Coulomb</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#physical_units"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="ABI_4700_TOF_TOF_mass_spectrometer">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="tandem_time_of_flight_mass_spectrometer"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Defines type of tandem mass spectrometer. Tandem time-of-flight spectrometer can perform ms and ms/ms type of analysis.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="ABI_4700_TOF_TOF_ms_raw_data"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="MS_analyzer_focus_mass">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="mass_units"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the center of the mass range or the center of the calibration curve for the given mass range.

[James &amp; Satya: 02/24/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf rdf:resource="#MS_analyzer_parameter"/>
  </owl:Class>
  <owl:Class rdf:ID="organism">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A biological species, such as Homo sapiens or Arabidopsis thaliana.
The taxonomic classification of a biological species are modeled in other ontologies. 
http://obo.sourceforge.net/cgi-bin/detail.cgi?ncbi_taxonomy
http://obo.sourceforge.net/cgi-bin/detail.cgi?newt

Instances of specific organisms may be specified iwithin ProPreO, but their complete systematic taxonomy should be found in these other ontologies.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#biological_continuant"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="experimental_chemical_mass">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the measured chemical mass of a particularmolecule or  ion.


[Dr. York &amp; Satya: 06/13/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="experimental_mass"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#MS_data_processing_parameter">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="MS_parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that is used by an application that processes mass spectral data</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="data_processing_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="inorganic_solvent_molecule">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A solvent molecule that does not contain carbon, e.g., water.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="solvent_molecule"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#protein">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:complementOf>
              <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                  <owl:Class rdf:ID="DNA_nucleotide_sequence"/>
                  <owl:Class rdf:ID="RNA_nucleotide_sequence"/>
                </owl:unionOf>
              </owl:Class>
            </owl:complementOf>
          </owl:Class>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:complementOf>
              <owl:Class rdf:about="#glycan_accession_number"/>
            </owl:complementOf>
          </owl:Class>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A biomolecule composed of amino acids connected by amide bonds.  In ProPreO, a protein is distinguished from an oligopeptide mainly by its size (proteins are larger, and so are polypeptides rather than oligopeptides) .

[Dr. York &amp; Satya: 06/10/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:complementOf>
              <owl:Class rdf:about="#polynucleotide_accession_number"/>
            </owl:complementOf>
          </owl:Class>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >polypeptide</rdfs:label>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#molecule"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="theoretical_monoisotopic_mass">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="theoretical_mass"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the theoretical (calculated) monoisotopic mass of a particular molecule or ion.


[Dr. York &amp; Satya: 06/13/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_instrumental_operating_parameter">
    <rdfs:subClassOf rdf:resource="#operating_parameter"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the operating state of the chromatograph during data collection</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#MS_instrumental_operating_parameter">
    <rdfs:subClassOf rdf:resource="#operating_parameter"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the operating state of the mass spectrometer during data collection</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_experimental_data_collection">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >c</rdfs:comment>
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#experimentally_measured_data_collection"/>
          <owl:Class rdf:about="#HPLC_data_collection"/>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:ID="MS_analyzer_scan_time">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the length of time for an MS or MS-MS scan.

[James &amp; Satya: 02/24/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MS_analyzer_parameter"/>
  </owl:Class>
  <owl:Class rdf:about="#electrical_potential_units">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the units of electrical potential</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#potential_units"/>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_operating_parameter_collection">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:unionOf rdf:parseType="Collection">
              <owl:Class rdf:about="#HPLC_parameter"/>
              <owl:Class rdf:about="#HPLC_gradient_program"/>
              <owl:Class rdf:about="#HPLC_gradient_time_point"/>
            </owl:unionOf>
          </owl:Class>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_data_part"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Class rdf:ID="operating_parameter_collection"/>
          <owl:Class rdf:about="#HPLC_data_collection"/>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of parameters required to perform or analyze an HPLC run.

[Dr. York &amp; Satya: 05/17/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="MS_detector">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_component"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >This is for self-manufactured or modified that are not found under the mass spectrometer instruments.

[James &amp; Satya: 02/24/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_standard_well_plate_autosampler">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC autosampler.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_autosampler"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Finnigan_LCQ_classic_mass_spectrometer">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:unionOf rdf:parseType="Collection">
              <owl:Class rdf:ID="Finnigan_ASC_ms-ms_peak_list"/>
              <owl:Class rdf:ID="Finnigan_Sequest_DTA_ms-ms_peak_list"/>
            </owl:unionOf>
          </owl:Class>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:ID="generates_ms-ms_peak_list"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="ion_trap_mass_spectrometer"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="Finnigan_LCQ_classic_ms_raw_data"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#molecule">
    <owl:equivalentClass>
      <owl:Restriction>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:ID="material_part_of"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="molecular_aggregate"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </owl:equivalentClass>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="chemical_entity"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An  individual molecule, categorized according to a few broadly defined classes.

[Dr. York &amp; Satya: 06/10/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:unionOf rdf:parseType="Collection">
              <owl:Class rdf:about="#molecular_parameter"/>
              <owl:Class rdf:about="#substance_accession_number"/>
            </owl:unionOf>
          </owl:Class>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="CCSD_ID">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#glycan_accession_number"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that specifies the unique identifier for a glycan structure in the CARBANK database.
URL: http://bssv01.lancs.ac.uk/gig/pages/gag/carbbank.htm#ccsd

[Dr. York &amp; Satya: 06/14/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#solution">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="mixture"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A mixture in the form of a homogeneous liquid contaning a solvent and at least one solute.

 A "solution" is_described_by one or more mixture_component_descriptor(s), each of which has two parts:  the component_amount and a substance_identifier that specifies the identity of the component.  This is a flexible way of describing solutions.  For example, a solution can be described as a mixture of two other solutions (e.g., buffer A and buffer B), in which case the mixture_component_descriptor(s) each specify the identity and amount of each of these buffers.  Alternatively, a solution can be described according to the concentrations of its solutes (dissolved molecules), each of which is specified by a mixture_component_descriptor.  In this case, complete description of the solution requires that the solvent be specified using the property has_solvent, which points to an instance of the class "solvent".
[Satya &amp; Will 03/02/06]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_APEX_Q_FT_mass_spectrometer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="hybrid_tandem_mass_spectrometer"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="Bruker_APEX_Q_FT_ms_raw_data"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="database_search_result_Mascot_dat_dataset">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="database_search_results_Mascot_data"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >This is a Mascot specific result file, produced from a database search - it is in text format. The sections of the file are delimited by a unique ID string and a Content-Type specification.

[James &amp; Satya: 03/29/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#molecular_sequence">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#molecular_parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the sequence of residues in a biopolymer.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="theoretical_ion_abundance">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the theoretical abundance of a particular ion.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ion_abundance"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="SemURI_module">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="annotation_associated_data_collection"/>
    </rdfs:subClassOf>
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Restriction>
            <owl:onProperty>
              <owl:TransitiveProperty rdf:about="#has_data_part"/>
            </owl:onProperty>
            <owl:someValuesFrom>
              <owl:Class rdf:ID="SemURI_concept_ID"/>
            </owl:someValuesFrom>
          </owl:Restriction>
          <owl:Restriction>
            <owl:someValuesFrom rdf:resource="#SemURI_instance_ID"/>
            <owl:onProperty>
              <owl:TransitiveProperty rdf:about="#has_data_part"/>
            </owl:onProperty>
          </owl:Restriction>
          <owl:Restriction>
            <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
            >2</owl:cardinality>
            <owl:onProperty>
              <owl:TransitiveProperty rdf:about="#has_data_part"/>
            </owl:onProperty>
          </owl:Restriction>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >This describes the two-component, basic building block of the Semantic URI provenance scheme.  The two components are:
1- SemURI_concept_ID 
2- SemURI_instance_ID

[will &amp; satya 03/03/06]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="ion_parameter">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the properties of an ion.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#substance_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#ion">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An electrically charged chemical species, which may be a single atom (e.g., Na+), or many atoms (e.g., NH4+).</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#chemical_entity"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#ion_parameter"/>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_esquire4000_ion_trap_ms_raw_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="component_amount">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#substance_amount"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the amount of a substance in a mixture.  This is expressed as some sort of fractional amount, such as weight percent, molarity, etc.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#hybrid_task">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A task that combines both physical and computational tasks.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#task"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#ESI_source">
    <rdfs:subClassOf rdf:resource="#MS_source"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >For for > microlitre/min flow rates.

[James &amp; Satya: 02/24/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#hardware">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An object manufactured to perform a specfic task.  Examples are bolts (which hold other objects together), computers (which execute software), and mass spectrometers (which separate and count ions based on their mass to charge ratios).</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#agent"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_esquire4000_ion_trap_mass_spectrometer">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ion_trap_mass_spectrometer"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#Bruker_esquire4000_ion_trap_ms_raw_data"/>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="quadrupole_time_of_flight_mass_spectrometer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem_mass_spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#tandem_mass_spectrometer"/>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_diode_array_detector">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_detector"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC detector.

[James &amp; Satya: 01/31/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_autoflex_MALDI_TOF_ms_raw_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="volume_units">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#physical_units"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter defining the physical units of time</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="size_exclusion_HPLC_column">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_column"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC column</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Spectrum_mill_application">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="Agilent_mass_spectrometer_data_processing_application"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Application software developed by Agilent for processing mass spectrometer data.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="eucaryotic_organism">
    <rdfs:subClassOf rdf:resource="#organism"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An organism whose cells contain a nucleus and internal membranes.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="ABI_Voyager_DE_Pro_MALDI_TOF_mass_spectrometer">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="ABI_Voyager_DE_Pro_MALDI_TOF_ms_raw_data"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of MALDI-TOF mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MALDI-TOF_mass_spectrometer"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Finnigan_LTQ_linear_ion_trap_ms_raw_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#database_search_output_data_collection">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection that is generated by a database search  with ms, ms-ms data

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#experimentally_measured_data_collection"/>
          <owl:Class rdf:about="#database_search_data_collection"/>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:ID="time_units">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#physical_units"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter defining the physical units of time</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_APEX_IV_mass_spectrometer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="Bruker_APEX_IV_ms_raw_data"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="fourier_transform_mass_spectrometer"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="process_associated_parameter">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that is classified according to the process that uses/creates/generates it.

[will &amp; satya 02/17/06]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="CARBANK_ID">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#glycan_accession_number"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that specifies the identifier for a glycan record in the CARBANK database.
URL: ftp://ncbi.nlm.nih.gov/repository/carbbank/

[Dr. York &amp; Satya: 06/14/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="mass">
    <rdfs:subClassOf rdf:resource="#ion_parameter"/>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#molecular_parameter"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Describes the molecular mass of a molecule or ion
.


[Dr. York &amp; Satya: 06/13/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >1</owl:cardinality>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="mass_volume_percent">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the amount of a particular substance in a solution. 
    The mass-volume percent of the substance is usually expressed as the number of grams of the substance divided by the number of milliliters of the solution, all divided by 100.  Sometimes the mass-volume percent is abbreviated %w/v.</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#component_amount"/>
  </owl:Class>
  <owl:Class rdf:ID="MALDI_source">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Defines the type of source.

[James &amp; Satya: 02/24/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MS_source"/>
  </owl:Class>
  <owl:Class rdf:ID="amino_acid_sequence">
    <rdfs:subClassOf rdf:resource="#molecular_sequence"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the sequence of amino acid residues of a peptide or protein.  Amino acids are listed starting at the N-terminus and continuing to the C-terminus using standard one-letter amino acid nomenclature. The name of the amino acid sequence is same as the sequence string.

[Dr. York &amp; Satya: 06/10/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="sort_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#transform_data"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A computational task involving the reordering of data elements according to a specific set of criteria.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="capillary_HPLC_pump">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC pump.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_pump"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Micromass_QTOF_2_quadrupole_time_of_flight_mass_spectrometer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="Micromass_QTOF_2_quadrupole_time_of_flight_ms_raw_data"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf rdf:resource="#quadrupole_time_of_flight_mass_spectrometer"/>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_ms-ms_peak_list"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:unionOf rdf:parseType="Collection">
              <owl:Class rdf:about="#Finnigan_Sequest_DTA_ms-ms_peak_list"/>
              <owl:Class rdf:ID="micromass_pkl_ms-ms_peak_list"/>
            </owl:unionOf>
          </owl:Class>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_column">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_component"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A matrix-containing tube  that is used for high-performance liquid chromatography.  The sample is separated into its components by injecting it into the column and elutimng with a solvent or buffer.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#MS_source_parameter">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the operating state of the mass spectrometer ion source during data collection

[Will &amp; Satya 02/15/06]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MS_instrumental_operating_parameter"/>
  </owl:Class>
  <owl:Class rdf:ID="Masslynx_proteinlynx_denovo_sequencing_results_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#denovo_sequencing_output_data_collection"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection produced by performing Proteinlynx denovo sequecing.

[James &amp; Satya: 03/29/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="MS_analyzer_mode">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the analyzer mode associated with a MS experiment. This parameter can have values of positive or negative. It describes the charge of the ions that are detected.

[James &amp; Satya: 02/24/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MS_analyzer_parameter"/>
  </owl:Class>
  <owl:Class rdf:ID="raw_gel_image_electrophoresis_data">
    <rdfs:subClassOf rdf:resource="#gel_electrophoresis_experimental_data_collection"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection generated by a gel electrophoresis experiment - this corresponds to an image of the gel, stored in a file format.

[James &amp; Satya: 03/29/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#Bruker_omniflex_MALDI_TOF_ms_raw_data">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#SemURI_concept_ID">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#SemURI_parameter"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >0</owl:cardinality>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#has_SemURI_concept_ID"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The first component of a semantic Universal Resource Identifier (semURI) module.  Each instance of this parameter maps the module to a specific concept in ProPreO.

[will &amp; satya 03/03/06]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="power_units">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#physical_units"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter defining the physical units of power</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="search_and_replace">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A computational task involving the identification of specific data elements and their replacement by another data element.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#transform_data"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="database_search_processing_parameter_collection">
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#operating_parameter_collection"/>
          <owl:Class rdf:about="#database_search_data_collection"/>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of parameters required to perform a database search with ms, ms-ms data.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="source_organ">
    <rdfs:subClassOf rdf:resource="#biological_source_parameter"/>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#refers_to_material_continuant"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="organ"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that specifies the organ from which the biological sample is taken.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="MS_data_collection">
    <rdfs:subClassOf rdf:resource="#process_associated_data_collection"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection used or generated by a mass spectrometry experiment</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Axiom_2">
    <owl:equivalentClass>
      <owl:Class>
        <owl:unionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#Proteinlynx_micromass_MALDI_data_processing_parameters_collection"/>
          <owl:Class rdf:about="#Proteinlynx_micromass_electrospray_data_processing_parameters_collection"/>
        </owl:unionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:ID="mixture_component_descriptor">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:someValuesFrom rdf:resource="#substance_identifier"/>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_data_part"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A pair of parameters that describes the amount of a particular component of a mixture.  For example "0.5 M NaCl" describes the amount of sodium chloride in a solution - there are two parts to this description - 0.5 M specifies the amount (half molar) - NaCl identifies the component that is present at that concentration.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_data_part"/>
        </owl:onProperty>
        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >2</owl:cardinality>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="substance_associated_data_collection"/>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_data_part"/>
        </owl:onProperty>
        <owl:someValuesFrom rdf:resource="#component_amount"/>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="enzyme_HPLC_column">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC column</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#HPLC_column"/>
  </owl:Class>
  <owl:Class rdf:ID="simulate_molecular_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The computational simulation of the structure, physical properties or behavior of a molecule, such as conformational trajectory or reaction kinetics.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#simulate_data"/>
  </owl:Class>
  <owl:Class rdf:about="#ms_output_data_collection">
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#experimentally_measured_data_collection"/>
          <owl:Class rdf:about="#MS_data_collection"/>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection generated by a mass spectrometer or mass spectral data processing application</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#MS_experimentally_measured_parameter">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that is measured during an MS experiment - E.G. the abundance of an ion having a particular m/z value.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#experimentally_measured_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="concentration_units">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#physical_units"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter defining the physical units of concentration</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_injection_loop_volume">
    <rdfs:subClassOf rdf:resource="#HPLC_instrumental_operating_parameter"/>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#volume_units"/>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that describes the injuection loop volume for an HPLC experiment.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="database_search_result_Mascot_HTML_dataset">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Following a Mascot db search, the data is saved in a HTML format. The results may further be converted into other representation formats.

[James &amp; Satya: 03/29/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#database_search_results_Mascot_data"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#database_search_results_Mascot_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection that is generated by a Matrix Science Mascot database search  with ms, ms-ms data</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#database_search_output_data_collection"/>
  </owl:Class>
  <owl:Class rdf:ID="normal-phase_HPLC_column">
    <rdfs:subClassOf rdf:resource="#HPLC_column"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC column</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#RNA_nucleotide_sequence">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the sequence of nucleotides in an RNA molecule.  Nucleotides are listed from the 5' end to the 3' end.</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#molecular_sequence"/>
  </owl:Class>
  <owl:Class rdf:about="#theoretical_mass">
    <rdfs:subClassOf rdf:resource="#mass"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the theoretical (calculated)  mass of a particular molecule or ion.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="data_file_URL">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="URL_parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A string parameter that contains the URL of a data file.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="binary_HPLC_pump">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC pump.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_pump"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="theoretical_ion_charge">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ion_charge"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the theoretical charge of a particular ion.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#URL_parameter">
    <rdfs:subClassOf rdf:resource="#annotation_parameter"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A string parameter that specifies the location of a resource (such as a data file) on the internet - I.e., a Universal Resource Locator</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="process_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The task of processing data using computational applications.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#computational_task"/>
  </owl:Class>
  <owl:Class rdf:ID="Micromass_MALDI_micro_MX_MALDI_TOF_ms_raw_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_raw_data_native_format"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#MALDI-TOF_mass_spectrometer">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_material_part"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:unionOf rdf:parseType="Collection">
              <owl:Class rdf:about="#TOF_analyzer"/>
              <owl:Class rdf:about="#MALDI_source"/>
              <owl:Class rdf:about="#MS_detector"/>
            </owl:unionOf>
          </owl:Class>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#mass_spectrometer"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A Matrix-Assisted-Laser-Desorption-Time-of-Flight mass spectrometer.  Such a spectrometer contains a MALDI source and a TOF analyzer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_standard_autosampler">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_autosampler"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC autosampler.

[James &amp; Satya: 01/31/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_detector_signal">
    <rdfs:subClassOf rdf:resource="#HPLC_experimentally_measured_parameter"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that describes the detector signal measured at a particular time of an HPLC experiment.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#ion_charge">
    <rdfs:subClassOf>

      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#electrical_charge_units"/>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf rdf:resource="#ion_parameter"/>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#int"/>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the (measured or theoretical) charge of a particular ion.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="quaternary_HPLC_pump">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC pump.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_pump"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="magnetic_sector_analyzer">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_analyzer"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of MS analyzer</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="GPS_Explorer_application">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Application software developed by Applied Bio Systems for processing mass spectrometer data.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="Applied_Bio_Systems_mass_spectrometer_data_processing_application"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="molecular_description">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:cardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#int"
        >1</owl:cardinality>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_value"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#molecular_parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Describes the molecule, its properties, origin etc.

[Dr. York &amp; Satya: 06/13/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#MS_operating_parameter_collection">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of parameters required to perform a task that generates or processes
 mass spectral data</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_data_part"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:unionOf rdf:parseType="Collection">
              <owl:Class rdf:about="#MS_parameter"/>
              <owl:Class rdf:about="#MS_operating_parameter_collection"/>
            </owl:unionOf>
          </owl:Class>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#operating_parameter_collection"/>
          <owl:Class rdf:about="#MS_data_collection"/>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:ID="gel_electrophoresis_processing_parameter_collection">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of parameters required to perform a gel electrophoresis experiment.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#operating_parameter_collection"/>
          <owl:Class rdf:about="#gel_electrophoresis_data_collection"/>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:about="#Proteinlynx_micromass_electrospray_data_processing_parameters_collection">
    <rdfs:subClassOf rdf:resource="#MS_data_processing_parameter_collection"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The collection of processing parameters used by Proteinlynx when converting a electrospray '.raw' file into a '.pkl' or a '.dta' file, when using Proteinlynx.

[James &amp; Satya: 04/01/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#record_raw_data">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="physical_task"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The task of recording raw data using an analytical instrument.

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_time_parameter">
    <rdfs:subClassOf rdf:resource="#HPLC_experimentally_measured_parameter"/>
    <rdfs:subClassOf rdf:resource="#HPLC_instrumental_operating_parameter"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that describes the time (measured from the start of the experiment) within a HPLC experiment that an event occurs.  This time parameter can be associated, for example, with a signal intensity or a buffer gradient condition.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="process_time_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_microscale_fraction_collector">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="HPLC_fraction_collector"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An HPLC fraction collector that directs the eluant from an microscale HPLC experiment.

[James &amp; Satya: 01/31/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_fluorenscence_detector">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_detector"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC detector.

[James &amp; Satya: 01/31/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="raw2mzXML_transformation">
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Restriction>
            <owl:hasValue>
              <SemURI_concept_ID rdf:ID="raw2mzXML_transformation_tsuka"/>
            </owl:hasValue>
            <owl:onProperty>
              <owl:ObjectProperty rdf:about="#has_SemURI_concept_ID"/>
            </owl:onProperty>
          </owl:Restriction>
          <owl:Restriction>
            <owl:allValuesFrom>
              <owl:Class rdf:ID="mzXML_ms_raw_data"/>
            </owl:allValuesFrom>
            <owl:onProperty>
              <owl:ObjectProperty rdf:ID="has_output_data"/>
            </owl:onProperty>
          </owl:Restriction>
          <owl:Restriction>
            <owl:allValuesFrom>
              <owl:Class rdf:ID="ms_raw_data"/>
            </owl:allValuesFrom>
            <owl:onProperty>
              <owl:ObjectProperty rdf:ID="has_input_experimental_data_collection"/>
            </owl:onProperty>
          </owl:Restriction>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >This task converts a raw mass spec data file into the mzXML format.</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#tranform_encoding_format"/>
  </owl:Class>
  <owl:Class rdf:ID="archaea">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Organisms, including the Crenarchaeota, Euryarchaeota and Korarchaeota, with a cell structure that is similar to other prokaryotes, but with some biochemical features  that are similar to eukaryotes, some similar to bacteria, and some unique to archaea.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#procaryotic_organism"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#MS_raw_data_native_format">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of mass spectral data that has NOT been computationally processed in any way.  That is, the raw output from the mass spectrometer. These may be of multiple formats

[James &amp; Satya: 03/22/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ms_raw_data"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#Agilent_mass_spectrometer_data_processing_application">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#MS_data_processing_application"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Application software developed by Agilent for processing mass spectrometer data.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#mass_units">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#physical_units"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter defining the physical units of mass</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="organic_solvent_molecule">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="small_organic_molecule"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A solvent molecule that contains carbon, e.g., methanol.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#solvent_molecule"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Axiom_5">
    <owl:equivalentClass>
      <owl:Class>
        <owl:unionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#Proteinlynx_micromass_MALDI_data_processing_parameters_collection"/>
          <owl:Class rdf:about="#Proteinlynx_micromass_electrospray_data_processing_parameters_collection"/>
        </owl:unionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:about="#physical_task">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#task"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A task that is performed by a human or physical instrument working on a 
physical sample.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#solvent">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="pure_substance"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The solvent of a solution, consisting of many copies of the solvent molecule.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#data_processing_parameter">
    <rdfs:subClassOf rdf:resource="#operating_parameter"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that is used by a data processing application</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="nanoflow_HPLC_pump">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC pump.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_pump"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_component">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A component of a hgh-performance liquid chromatograph</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#instrument_component"/>
  </owl:Class>
  <owl:Class rdf:ID="PerSeptive_PKS_51_ms-ms_peak_list">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection consisting of a list of precursor ion masses and associated fragment ion masses from an ms/ms experiment.

PSD peak lists exported from Grams as .PKS files contain data from a single PSD spectrum. Since the .PKS format does not include details of the precursor peptide m/z, this information must be entered manually into the PRECURSOR and CHARGE form fields. This limitation also means that multiple spectra cannot be merged into a single data file. 
(Reference: http://www.matrixscience.com/help/data_file_help.html#QTOF)

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="ms-ms_peak_list"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#ABI_Voyager_DE_Pro_MALDI_TOF_ms_raw_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this instrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MS_raw_data_native_format"/>
  </owl:Class>
  <owl:Class rdf:ID="classify_data">
    <rdfs:subClassOf rdf:resource="#process_data"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The computational processing in which data elements are matched to a spcific group to which they belong.  This  includes:
a) identifying molecules associated with experimental data features such as ion masses (e.g., MASCOT analysis)
b) categorize features in data using a set of parameters. For example, distinguish peptides from glycopeptides

[Dr. York &amp; Satya: 11/21/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#experimentally_measured_data_collection">
    <rdfs:subClassOf rdf:resource="#data_collection"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >This describes collections of experimental (measured) data, either raw or processed. 
    Such data can serve as the input to a data processing task or the output 
    of an experimental measurement or computational task.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="trypsin">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="proteolytic_enzyme"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Class of related proteolytic enzymes that cleave after basic amino acids K &amp; R except when followed by P.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#mixture">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A molecular aggregate composed of more than one type of molecule.

 A mixture is_described_by one or more mixture_component_descriptor(s), each of
which has two parts:  the component_amount and a substance_identifier that specifies the component itself.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#mixture_component_descriptor"/>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#molecular_aggregate"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="separate_by_filtration">
    <rdfs:subClassOf>
      <owl:Class rdf:ID="separate_components"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Separate components of a mixture by filtration.  The filter allows some components to pass through while retaining other components.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="mass_percent">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the amount of a particular substance in a mixture. 
    The mass percent of the substance is its percent contribution to the  
    total mass of the mixture.  Sometimes mass percent is called weight/weight 
    percent, and abbreviated %w/w.</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#component_amount"/>
  </owl:Class>
  <owl:Class rdf:ID="Axiom_1">
    <owl:equivalentClass>
      <owl:Class>
        <owl:unionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#Proteinlynx_micromass_MALDI_data_processing_parameters_collection"/>
          <owl:Class rdf:about="#Proteinlynx_micromass_electrospray_data_processing_parameters_collection"/>
        </owl:unionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:about="#analytical_instrument">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An analytical instrument is a piece of hardware designed to measure a parameter or analyze a sample.</rdfs:comment>
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#hardware"/>
          <owl:Restriction>
            <owl:allValuesFrom rdf:resource="#instrument_component"/>
            <owl:onProperty>
              <owl:TransitiveProperty rdf:about="#has_material_part"/>
            </owl:onProperty>
          </owl:Restriction>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:about="#tandem_time_of_flight_mass_spectrometer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem_mass_spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#tandem_mass_spectrometer"/>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_microQTOF_quadrupole_time_of_flight_ms_raw_data">
    <rdfs:subClassOf rdf:resource="#MS_raw_data_native_format"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Axiom_3">
    <owl:equivalentClass>
      <owl:Class>
        <owl:unionOf rdf:parseType="Collection">
          <owl:Class rdf:about="#HPLC_variable_wavelength_detector"/>
          <owl:Class rdf:about="#HPLC_multiwavelength_detector"/>
          <owl:Class rdf:about="#HPLC_diode_array_detector"/>
          <owl:Class rdf:about="#HPLC_fluorenscence_detector"/>
        </owl:unionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:about="#Micromass_Quatro_micro_triple_quadrupole_ms_raw_data">
    <rdfs:subClassOf rdf:resource="#MS_raw_data_native_format"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_chromatogram">
    <owl:equivalentClass>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#HPLC_time_signal_pair"/>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_data_part"/>
        </owl:onProperty>
      </owl:Restriction>
    </owl:equivalentClass>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A data collection (chromatogram) generated by an HPLC experiment -This typically consists of a collection of time/signal intensity pairs 

[James &amp; Satya: 03/29/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#HPLC_experimental_data_collection"/>
  </owl:Class>
  <owl:Class rdf:ID="data_processing_application">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#agent"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Application software used in processing/manipulating data.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_esquire6000_ion_trap_mass_spectrometer">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#Bruker_esquire6000_ion_trap_ms_raw_data"/>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ion_trap_mass_spectrometer"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#MS_instrument_setup_parameter_collection">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#MS_instrumental_operating_parameter"/>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_data_part"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of instrumental parameters required to record mass spectral data

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MS_operating_parameter_collection"/>
  </owl:Class>
  <owl:Class rdf:about="#ABI_4700_TOF_TOF_ms_raw_data">
    <rdfs:subClassOf rdf:resource="#MS_raw_data_native_format"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this instrument.

[James &amp; Satya: 03/22/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#molecular_aggregate">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An aggregate of molecules, which may or may not be homogeneous.  E.G.:
 a liter of water (homogeneous)
 a pound of wheat flour (heterogeneous)
 a milligram of extracted protein (heterogeneous)

[will &amp; satya 03/02/06]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#chemical_entity"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#substance_parameter">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that describes a physical substance such as a buffer, gas etc.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#experimentally_measured_parameter">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#parameter"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An experimentally measured parameter, either raw or processed. (E.G., signal intensity)
    A collection of such parameters can serve as the input to a data processing task or the output 
    of an experimental measurement or computational task.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_BioTOF_Q_quadrupole_time_of_flight_mass_spectrometer">
    <rdfs:subClassOf rdf:resource="#quadrupole_time_of_flight_mass_spectrometer"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="Bruker_BioTOF_Q_quadrupole_time_of_flight_ms_raw_data"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="MS_maxent3_number_of_ensemble_members">
    <rdfs:subClassOf rdf:resource="#MS_data_processing_parameter"/>
  </owl:Class>
  <owl:Class rdf:ID="separate_by_dialysis">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Separate components of a mixture by dialysis.  The dialysis membrane allows some components to pass through while retaining other components.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#separate_components"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#hybrid_tandem_mass_spectrometer">
    <rdfs:subClassOf rdf:resource="#tandem_mass_spectrometer"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem_mass_spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="MALDI_matrix">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:TransitiveProperty rdf:about="#has_material_part"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="small_molecule"/>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf rdf:resource="#molecular_aggregate"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A molecular aggragate that is used in a MALDI source.  The MALDI matrix absorbs energy from the laser, and this energy promotes transfer to the gas phase and ionizaton of the analyte.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="CHEBI_ID">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#substance_accession_number"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that corresponds to the CHEBI ID from the ChEBI Ontology
http://www.ebi.ac.uk/chebi/</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="MS_maxent3_compress_value_option">
    <rdfs:subClassOf rdf:resource="#MS_data_processing_parameter"/>
  </owl:Class>
  <owl:Class rdf:about="#procaryotic_organism">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An organism whose cells do not have a nucleus or internal membranes.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#organism"/>
  </owl:Class>
  <owl:Class rdf:about="#Bruker_APEX_Q_FT_ms_raw_data">
    <rdfs:subClassOf rdf:resource="#MS_raw_data_native_format"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The raw data output from this intrument.

[James &amp; Satya: 03/27/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="separate_by_HPLC">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The process of separating components by high-performance liquid chromatography.</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#separate_by_chromatography"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#mzXML_ms_raw_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of mass spectral data that has NOT been computationally processed, except that it has been converted to mzXML format</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="MS_raw_data_converted_format"/>
    </rdfs:subClassOf>
    <owl:equivalentClass>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#has_SemURI_concept_ID"/>
        </owl:onProperty>
        <owl:hasValue>
          <SemURI_concept_ID rdf:ID="mzXML_ms_raw_data_tsuka"/>
        </owl:hasValue>
      </owl:Restriction>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:ID="fragment_peptide_N_terminus_index">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the index (within the parent protein) of the N- terminus of a fragment peptide.

[will &amp; satya 04/25/06]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#molecular_parameter"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="MS_analyzer_mass_range_max">
    <rdfs:subClassOf rdf:resource="#MS_analyzer_parameter"/>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#mass_units"/>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that defines the maximum mass range associated with a MS experiment. Mass range is determined by the user and the instrument. It typically has a value from 0 to 500,000.


[James &amp; Satya: 02/24/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_gradient_time_point">
    <rdfs:subClassOf rdf:resource="#HPLC_operating_parameter_collection"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of parameters that defines a HPLC run time and the associated buffer mixture that comprises the eluent at that time. It can have multiple values of component portion for that time value.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
    <owl:equivalentClass>
      <owl:Class>
        <owl:intersectionOf rdf:parseType="Collection">
          <owl:Restriction>
            <owl:onProperty>
              <owl:TransitiveProperty rdf:about="#has_data_part"/>
            </owl:onProperty>
            <owl:someValuesFrom rdf:resource="#HPLC_time_parameter"/>
          </owl:Restriction>
          <owl:Restriction>
            <owl:someValuesFrom rdf:resource="#mixture_component_descriptor"/>
            <owl:onProperty>
              <owl:TransitiveProperty rdf:about="#has_data_part"/>
            </owl:onProperty>
          </owl:Restriction>
        </owl:intersectionOf>
      </owl:Class>
    </owl:equivalentClass>
  </owl:Class>
  <owl:Class rdf:about="#Proteinlynx_micromass_MALDI_data_processing_parameters_collection">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >The collection of processing parameters used by Proteinlynx when converting a MALDI '.raw' file into a '.pkl' or a '.dta' file, when using Proteinlynx.

[James &amp; Satya: 04/01/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MS_data_processing_parameter_collection"/>
  </owl:Class>
  <owl:Class rdf:ID="volume_percent">
    <rdfs:subClassOf rdf:resource="#component_amount"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the amount of a particular substance in a mixture. 
    The volume percent of the substance is its percent contribution to the  
    total volume of the mixture.  Sometimes volume percent is called volume/volume 
    percent, and abbreviated %v/v.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#molecular_parameter">
    <rdfs:subClassOf rdf:resource="#substance_parameter"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter describing the identity or a physical property of a molecule.

[James &amp; Satya: 04/01/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_parameter">
    <rdfs:subClassOf rdf:resource="#process_associated_parameter"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that is used/created/generated during the acquisition or processing of HPLC data</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#annotation_associated_data_collection">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >a data collection that is used to annotate other data</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#data_collection"/>
  </owl:Class>
  <owl:Class rdf:ID="HPLC_flowrate">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class rdf:ID="flowrate_units"/>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:FunctionalProperty rdf:about="#has_units"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A parameter that describes the eluant flow rate for an HPLC experiment.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#HPLC_instrumental_operating_parameter"/>
  </owl:Class>
  <owl:Class rdf:about="#MS_raw_data_converted_format">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ms_raw_data"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of mass spectral data that has NOT been computationally processed, except that its digital format has been modified</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="glycan">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:complementOf>
              <owl:Class rdf:about="#polynucleotide_accession_number"/>
            </owl:complementOf>
          </owl:Class>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A biomolecule composed of glycosyl residues.  A glycan is a type of carbohydrate molecule.

[Dr. York &amp; Satya: 06/10/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:complementOf>
              <owl:Class rdf:about="#protein_accession_number"/>
            </owl:complementOf>
          </owl:Class>
        </owl:allValuesFrom>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:subClassOf rdf:resource="#molecule"/>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom>
          <owl:Class>
            <owl:complementOf rdf:resource="#molecular_sequence"/>
          </owl:Class>
        </owl:allValuesFrom>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#is_described_by"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_microQTOF_quadrupole_time_of_flight_mass_spectrometer">
    <rdfs:subClassOf rdf:resource="#quadrupole_time_of_flight_mass_spectrometer"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
        <owl:allValuesFrom rdf:resource="#Bruker_microQTOF_quadrupole_time_of_flight_ms_raw_data"/>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#substance_associated_data_collection">
    <rdfs:subClassOf rdf:resource="#data_collection"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >a data collection that describes the physical substances such as buffers, gases etc.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_fraction_collector">
    <rdfs:subClassOf rdf:resource="#HPLC_component"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >An HPLC instrument component  that directs the eluant from the HPLC column to a series of separate vessels (tubes of wells).  The collector may direct the eluant to different vessels based on elution time, detector response, or some other criterion.</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_variable_wavelength_detector">
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_detector"/>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC detector.

[James &amp; Satya: 01/31/05]</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:ID="ms_processed_data">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A collection of mass spectral data that has been computationally processed - E.G. a peak list

[James &amp; Satya: 03/22/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#ms_output_data_collection"/>
  </owl:Class>
  <owl:Class rdf:about="#MS_component">
    <rdfs:subClassOf rdf:resource="#instrument_component"/>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A component of a mass spectrometer</rdfs:comment>
  </owl:Class>
  <owl:Class rdf:about="#proteolytic_enzyme">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A  protein that catalyzes the cleavage of peptide bonds in proteins to generate peptides.

[Dr. York &amp; Satya: 06/28/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#enzyme"/>
  </owl:Class>
  <owl:Class rdf:ID="Micromass_MALDI_micro_MX_MALDI_TOF_mass_spectrometer">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of MALDI-TOF mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#MALDI-TOF_mass_spectrometer"/>
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#Micromass_MALDI_micro_MX_MALDI_TOF_ms_raw_data"/>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:about="#HPLC_multiwavelength_detector">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC detector.

[James &amp; Satya: 01/31/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#HPLC_detector"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="MS_min_peak_width_at_half_height_mass_measure_value">
    <rdfs:subClassOf rdf:resource="#MS_data_processing_parameter"/>
  </owl:Class>
  <owl:Class rdf:ID="Bruker_HCT_ion_trap_mass_spectrometer">
    <rdfs:subClassOf>
      <owl:Restriction>
        <owl:allValuesFrom rdf:resource="#Bruker_HCT_ion_trap_ms_raw_data"/>
        <owl:onProperty>
          <owl:ObjectProperty rdf:about="#generates_raw_data"/>
        </owl:onProperty>
      </owl:Restriction>
    </rdfs:subClassOf>
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of tandem mass spectrometer.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:about="#ion_trap_mass_spectrometer"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="Turbo_Sequest_application">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >Application software developed by ThermoElectron for processing mass spectrometer data.

[James &amp; Satya: 03/27/05]</rdfs:comment>
    <rdfs:subClassOf>
      <owl:Class rdf:ID="ThermoElectron_mass_spectrometer_data_processing_application"/>
    </rdfs:subClassOf>
  </owl:Class>
  <owl:Class rdf:ID="weak_anion_exchange_HPLC_column">
    <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string"
    >A type of HPLC column</rdfs:comment>
    <rdfs:subClassOf rdf:resource="#HPLC_column"/>
  </owl:Class>
  <owl:Class r