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- The BioCyc
Knowledge Library is a collection of Pathway/Genome Databases.
Each database in the BioCyc collection describes the genome and
metabolic pathways of a single organism, with the exception of
the MetaCyc database, which is a reference source on metabolic
pathways from many organisms.
- EcoCyc,
a part of the BioCyc library, is a scientific database for the
bacterium Escherichia coli. The EcoCyc project performs literature-based
curation of the entire E. coli genome, and of E. coli transcriptional
regulation, transporters, and metabolic pathways.
- EMBL
at the European BioInformatics
Institute:
The EMBL
Nucleotide Sequence Database (also known as EMBL-Bank) constitutes
Europe's primary nucleotide sequence resource. Main sources for
DNA and RNA sequences are direct submissions from individual researchers,
genome sequencing projects and patent applications.
- EpoDB
(Erythropoiesis database) is a database of genes that relate to
vertebrate red blood cells. It includes DNA sequence, structural
features, protein information, gene expression information and
transcription factor binding sites.
- FlyBase:
A Database of the Drosophila Genome
- GeneX-Lite
strives to make the greatest use of gene expression data by integrating
several complementary technologies to create a system that may
be utilized by a large institution or an individual researcher's
private lab.
- IMGT, the
international ImMunoGeneTics information system®, is a high-quality
integrated knowledge resource specializing in immunoglobulins
(IG), T cell receptors (TR), major histocompatibility complex
(MHC) and related proteins of the immune system of human and other
vertebrate species
- InterPro
at the European BioInformatics
Institute: InterPro is a database of protein families, domains
and functional sites in which identifiable features found in known
proteins can be applied to unknown protein sequences
- MIPS:
munich information center for protein sequences.
- mmCIF
- macromolecular Crystallographic Information File
- The Mouse
Anatomical Dictionary Browser on the Mouse
Genome Informatics site
- PharmGKB
is an integrated resource about how variation in human
genes leads to variation in our response to drugs.
- Proteome
BioKnowledge Library
Six database volumes of biological information about
proteins comprise Incyte's Proteome BioKnowledge Library. Each
volume focuses on a different organism important in pharmaceutical
research.
HumanPSD - A survey of human, mouse and rat proteins
GPCR-PD - G protein-coupled receptors and interacting
proteins for human, mouse and rat
YPD - Saccharomyces cerevisiae
PombePD - Schizosaccharomyces pombe
WormPD - Caenorhabditis elegans
MycoPathPD - Human Fungal Pathogens
- RiboWeb
is a prototype for new structural information resources that tightly
link models and their coordinates with experimental (and other)
data sources. The project initially focused on the structure of
the prokaryotic 30S ribosomal subunit, which initiates the translation
of mRNA into protein and is the site of action of numerous antibiotics;
the project has since been expanded to include structural data
pertaining to the entire ribosome of prokaryotes (but primarily
E. coli).
- Swiss-Prot
is a curated protein sequence database which strives to provide
a high level of annotations (such as the description of the function
of a protein, its domains structure, post-translational modifications,
variants, etc.), a minimal level of redundancy and high level
of integration with other databases
- The TAMBIS
project
TAMBIS aims to aid researchers in biological science by providing
a single access point for biological information sources round
the world. The access point will be a single interface (via the
World Wide Web) which acts as a single information source. It
will find appropriate sources of information for user queries
and phrase the user questions for each source, returning the results
in a consistent manner which will include details of the information
source.
- MeSH
- Medical Subject Headings at NLM
- PROW
- NLM's Proteine Review on the Web
- UMLS
- NLM's Unified Medical Language System (UMLS) project develops
and distributes multi-purpose, electronic "Knowledge Sources"
and associated lexical programs.
- The Gene Ontology
(GO) Consortium
- CBIL
Controlled Vocabulary Terms for human anatomy.
- Enzyme
Nomenclature from the Nomenclature Committee
of the International Union of Biochemistry and Molecular Biology
(NC-IUBMB)
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