bio-Ontologies, Databases
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  • The BioCyc Knowledge Library is a collection of Pathway/Genome Databases. Each database in the BioCyc collection describes the genome and metabolic pathways of a single organism, with the exception of the MetaCyc database, which is a reference source on metabolic pathways from many organisms.
  • EcoCyc, a part of the BioCyc library, is a scientific database for the bacterium Escherichia coli. The EcoCyc project performs literature-based curation of the entire E. coli genome, and of E. coli transcriptional regulation, transporters, and metabolic pathways.
  • EMBL at the European BioInformatics Institute:
    The EMBL Nucleotide Sequence Database (also known as EMBL-Bank) constitutes Europe's primary nucleotide sequence resource. Main sources for DNA and RNA sequences are direct submissions from individual researchers, genome sequencing projects and patent applications.
  • EpoDB (Erythropoiesis database) is a database of genes that relate to vertebrate red blood cells. It includes DNA sequence, structural features, protein information, gene expression information and transcription factor binding sites.
  • FlyBase: A Database of the Drosophila Genome
  • GeneX-Lite strives to make the greatest use of gene expression data by integrating several complementary technologies to create a system that may be utilized by a large institution or an individual researcher's private lab.
  • IMGT, the international ImMunoGeneTics information system®, is a high-quality integrated knowledge resource specializing in immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex (MHC) and related proteins of the immune system of human and other vertebrate species
  • InterPro at the European BioInformatics Institute: InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences
  • MIPS: munich information center for protein sequences.
  • mmCIF - macromolecular Crystallographic Information File
  • The Mouse Anatomical Dictionary Browser on the Mouse Genome Informatics site
  • PharmGKB is an integrated resource about how variation in human genes leads to variation in our response to drugs.
  • Proteome BioKnowledge Library
    Six database volumes of biological information about proteins comprise Incyte's Proteome BioKnowledge Library. Each volume focuses on a different organism important in pharmaceutical research.
    HumanPSD - A survey of human, mouse and rat proteins
    GPCR-PD - G protein-coupled receptors and interacting proteins for human, mouse and rat
    YPD - Saccharomyces cerevisiae
    PombePD - Schizosaccharomyces pombe
    WormPD - Caenorhabditis elegans
    MycoPathPD - Human Fungal Pathogens
  • RiboWeb is a prototype for new structural information resources that tightly link models and their coordinates with experimental (and other) data sources. The project initially focused on the structure of the prokaryotic 30S ribosomal subunit, which initiates the translation of mRNA into protein and is the site of action of numerous antibiotics; the project has since been expanded to include structural data pertaining to the entire ribosome of prokaryotes (but primarily E. coli).
  • Swiss-Prot is a curated protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases
  • The TAMBIS project
    TAMBIS aims to aid researchers in biological science by providing a single access point for biological information sources round the world. The access point will be a single interface (via the World Wide Web) which acts as a single information source. It will find appropriate sources of information for user queries and phrase the user questions for each source, returning the results in a consistent manner which will include details of the information source.
  • MeSH - Medical Subject Headings at NLM
  • PROW - NLM's Proteine Review on the Web
  • UMLS - NLM's Unified Medical Language System (UMLS) project develops and distributes multi-purpose, electronic "Knowledge Sources" and associated lexical programs.
  • The Gene Ontology (GO) Consortium
  • CBIL Controlled Vocabulary Terms for human anatomy.
  • Enzyme Nomenclature from the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)